The world has changed in profound and unique ways. There is a new way of working with new rules and a new way of thinking when it comes to how value is measured. The recent virus pandemic has caused many businesses to change the way their people work, and businesses must rethink how to succeed in the post-pandemic world. Against this backdrop, abilities to deal with other future business interruptions going forwards must be built into the way we set up systems, processes, and services. One also must be sensitive to swapping long-term strategy for short-term survival tactics, thereby opening the risk of making detrimental or limiting shortterm decisions. This paper considers a number of these approaches and business opportunities, and how modern IT can be harnessed to enable a new era of Business operation, competitiveness, efficiency, and innovation.